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A functional variant in FCRL3 is associated with higher FcRL3 expression on T cell subsets and rheumatoid arthritis disease activity
OBJECTIVE: CD4(+)FoxP3(+) regulatory T cells (T(reg)) suppress effector T cells and prevent autoimmune disease. T(reg) function is deficient in active rheumatoid arthritis (RA), a loss which may play a role in the pathogenesis of this disease. We previously showed that a single nucleotide polymorphi...
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| Main Authors: | , , , , , |
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| Formato: | Artigo |
| Idioma: | Inglês |
| Publicado em: |
2012
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| Assuntos: | |
| Acesso em linha: | https://ncbi.nlm.nih.gov/pmc/articles/PMC3374037/ https://ncbi.nlm.nih.gov/pubmed/22392608 https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1002/art.34457 |
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