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Prediction of protease substrates using sequence and structure features

Motivation:Granzyme B (GrB) and caspases cleave specific protein substrates to induce apoptosis in virally infected and neoplastic cells. While substrates for both types of proteases have been determined experimentally, there are many more yet to be discovered in humans and other metazoans. Here, we...

पूर्ण विवरण

में बचाया:
ग्रंथसूची विवरण
मुख्य लेखकों: Barkan, David T., Hostetter, Daniel R., Mahrus, Sami, Pieper, Ursula, Wells, James A., Craik, Charles S., Sali, Andrej
स्वरूप: Artigo
भाषा:Inglês
प्रकाशित: Oxford University Press 2010
विषय:
ऑनलाइन पहुंच:https://ncbi.nlm.nih.gov/pmc/articles/PMC2894511/
https://ncbi.nlm.nih.gov/pubmed/20505003
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1093/bioinformatics/btq267
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