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Prediction of protease substrates using sequence and structure features
Motivation:Granzyme B (GrB) and caspases cleave specific protein substrates to induce apoptosis in virally infected and neoplastic cells. While substrates for both types of proteases have been determined experimentally, there are many more yet to be discovered in humans and other metazoans. Here, we...
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| Main Authors: | , , , , , , |
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| Format: | Artigo |
| Sprog: | Inglês |
| Udgivet: |
Oxford University Press
2010
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| Fag: | |
| Online adgang: | https://ncbi.nlm.nih.gov/pmc/articles/PMC2894511/ https://ncbi.nlm.nih.gov/pubmed/20505003 https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1093/bioinformatics/btq267 |
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