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Apoptosis blocks Beclin 1-dependent autophagosome synthesis – an effect rescued by Bcl-xL
Apoptotic cell death is mediated by caspase activation. Autophagy involves the sequestration of cytoplasmic contents into autophagosomes for traffic to lysosomes for degradation. While autophagy is antiapoptotic, increased numbers of autophagosomes have been associated with forms of non-apoptotic ce...
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| 主要な著者: | , |
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| フォーマット: | Artigo |
| 言語: | Inglês |
| 出版事項: |
2009
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| 主題: | |
| オンライン･アクセス: | https://ncbi.nlm.nih.gov/pmc/articles/PMC2894406/ https://ncbi.nlm.nih.gov/pubmed/19713971 https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1038/cdd.2009.121 |
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