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A Nucleus-based Quality Control Mechanism for Cytosolic Proteins
Intracellular quality control systems monitor protein conformational states. Irreversibly misfolded proteins are cleared through specialized degradation pathways. Their importance is underscored by numerous pathologies caused by aberrant proteins. In the cytosol, where most proteins are synthesized,...
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| Autores principales: | , , |
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| Formato: | Artigo |
| Lenguaje: | Inglês |
| Publicado: |
The American Society for Cell Biology
2010
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| Materias: | |
| Acceso en línea: | https://ncbi.nlm.nih.gov/pmc/articles/PMC2893977/ https://ncbi.nlm.nih.gov/pubmed/20462951 https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1091/mbc.E10-02-0111 |
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