Interplay of Substrate Retention and Export Signals in Endoplasmic Reticulum Quality Control

BACKGROUND: Endoplasmic reticulum (ER) quality control mechanisms are part of a comprehensive system to manage cell stress. The flux of molecules is monitored to retain folding intermediates and target misfolded molecules to ER-associated degradation (ERAD) pathways. The mechanisms of sorting remain...

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Detalles Bibliográficos
Main Authors: Kawaguchi, Shinichi, Hsu, Chia-Ling, Ng, Davis T. W.
Formato: Artigo
Idioma:Inglês
Publicado: Public Library of Science 2010
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Research Article
Acceso en liña:https://ncbi.nlm.nih.gov/pmc/articles/PMC2991357/
https://ncbi.nlm.nih.gov/pubmed/21151492
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1371/journal.pone.0015532
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