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Interplay of Substrate Retention and Export Signals in Endoplasmic Reticulum Quality Control
BACKGROUND: Endoplasmic reticulum (ER) quality control mechanisms are part of a comprehensive system to manage cell stress. The flux of molecules is monitored to retain folding intermediates and target misfolded molecules to ER-associated degradation (ERAD) pathways. The mechanisms of sorting remain...
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| Main Authors: | , , |
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| Format: | Artigo |
| Sprog: | Inglês |
| Udgivet: |
Public Library of Science
2010
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| Fag: | |
| Online adgang: | https://ncbi.nlm.nih.gov/pmc/articles/PMC2991357/ https://ncbi.nlm.nih.gov/pubmed/21151492 https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1371/journal.pone.0015532 |
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