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Endoplasmic Reticulum Protein Quality Control in β cells
Type 1 and type 2 diabetes are associated with loss of β cell function. Optimal β cell function is linked to protein homeostasis in the endoplasmic reticulum (ER). Here, we review the roles of ER protein quality-control mechanisms, including the unfolded protein response (UPR), autophagy (specifical...
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| Publicado en: | Semin Cell Dev Biol |
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| Main Authors: | , , |
| Formato: | Artigo |
| Idioma: | Inglês |
| Publicado: |
2020
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| Assuntos: | |
| Acceso en liña: | https://ncbi.nlm.nih.gov/pmc/articles/PMC7321887/ https://ncbi.nlm.nih.gov/pubmed/32402517 https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1016/j.semcdb.2020.04.006 |
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