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Endoplasmic Reticulum Protein Quality Control in β cells

Type 1 and type 2 diabetes are associated with loss of β cell function. Optimal β cell function is linked to protein homeostasis in the endoplasmic reticulum (ER). Here, we review the roles of ER protein quality-control mechanisms, including the unfolded protein response (UPR), autophagy (specifical...

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Detalhes bibliográficos
Publicado no:Semin Cell Dev Biol
Main Authors: Shrestha, Neha, Reinert, Rachel B., Qi, Ling
Formato: Artigo
Idioma:Inglês
Publicado em: 2020
Assuntos:
Acesso em linha:https://ncbi.nlm.nih.gov/pmc/articles/PMC7321887/
https://ncbi.nlm.nih.gov/pubmed/32402517
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1016/j.semcdb.2020.04.006
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