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A Nucleus-based Quality Control Mechanism for Cytosolic Proteins
Intracellular quality control systems monitor protein conformational states. Irreversibly misfolded proteins are cleared through specialized degradation pathways. Their importance is underscored by numerous pathologies caused by aberrant proteins. In the cytosol, where most proteins are synthesized,...
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| Main Authors: | , , |
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| Formato: | Artigo |
| Idioma: | Inglês |
| Publicado em: |
The American Society for Cell Biology
2010
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| Assuntos: | |
| Acesso em linha: | https://ncbi.nlm.nih.gov/pmc/articles/PMC2893977/ https://ncbi.nlm.nih.gov/pubmed/20462951 https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1091/mbc.E10-02-0111 |
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