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Neutron Structure of Human Carbonic Anhydrase II: Implications for Proton Transfer
Human carbonic anhydrase II (HCA II) catalyzes the reversible hydration of carbon dioxide to form bicarbonate and a proton. Despite many high-resolution X-ray crystal structures, mutagenesis, and kinetic data, the structural details of the active site, especially the proton transfer pathway, are unc...
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| Main Authors: | , , , , , , |
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| Formato: | Artigo |
| Idioma: | Inglês |
| Publicado em: |
2010
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| Assuntos: | |
| Acesso em linha: | https://ncbi.nlm.nih.gov/pmc/articles/PMC2893723/ https://ncbi.nlm.nih.gov/pubmed/20025241 https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1021/bi901995n |
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