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Preliminary joint neutron and X-ray crystallographic study of human carbonic anhydrase II

Carbonic anhydrases catalyze the interconversion of CO(2) to HCO(3) (−), with a subsequent proton-transfer (PT) step. PT proceeds via a proposed hydrogen-bonded water network in the active-site cavity that is stabilized by several hydrophilic residues. A joint X-ray and neutron crystallographic stud...

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Detalhes bibliográficos
Main Authors: Fisher, S. Z., Kovalevsky, A. Y., Domsic, J. F., Mustyakimov, M., Silverman, D. N., McKenna, R., Langan, Paul
Formato: Artigo
Idioma:Inglês
Publicado em: International Union of Crystallography 2009
Assuntos:
Acesso em linha:https://ncbi.nlm.nih.gov/pmc/articles/PMC2675594/
https://ncbi.nlm.nih.gov/pubmed/19407386
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1107/S1744309109013086
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