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Production and X-ray crystallographic analysis of fully deuterated human carbonic anhydrase II
Human carbonic anhydrase II (HCA II) is a zinc metalloenzyme that catalyzes the reversible hydration and dehydration of carbon dioxide and bicarbonate, respectively. The rate-limiting step in catalysis is the intramolecular transfer of a proton between the zinc-bound solvent (H(2)O/OH(−)) and the pr...
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| 主要な著者: | , , , , , , |
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| フォーマット: | Artigo |
| 言語: | Inglês |
| 出版事項: |
International Union of Crystallography
2005
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| 主題: | |
| オンライン･アクセス: | https://ncbi.nlm.nih.gov/pmc/articles/PMC2150928/ https://ncbi.nlm.nih.gov/pubmed/16511248 https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1107/S1744309105038248 |
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