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The Saccharomyces cerevisiae RAD9, RAD17 and RAD24 genes are required for suppression of mutagenic post-replicative repair during chronic DNA damage
In Saccharomyces cerevisiae, a DNA damage checkpoint in the S phase is responsible for delaying DNA replication in response to genotoxic stress. This pathway is partially regulated by the checkpoint proteins Rad9, Rad17 and Rad24. Here, we describe a novel hypermutable phenotype for rad9Δ, rad17Δ an...
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| Autores principales: | , , , , |
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| Formato: | Artigo |
| Lenguaje: | Inglês |
| Publicado: |
2010
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| Materias: | |
| Acceso en línea: | https://ncbi.nlm.nih.gov/pmc/articles/PMC2893243/ https://ncbi.nlm.nih.gov/pubmed/20472512 https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1016/j.dnarep.2010.04.007 |
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