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The Saccharomyces cerevisiae RAD9, RAD17 and RAD24 genes are required for suppression of mutagenic post-replicative repair during chronic DNA damage

In Saccharomyces cerevisiae, a DNA damage checkpoint in the S phase is responsible for delaying DNA replication in response to genotoxic stress. This pathway is partially regulated by the checkpoint proteins Rad9, Rad17 and Rad24. Here, we describe a novel hypermutable phenotype for rad9Δ, rad17Δ an...

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Bibliografische gegevens
Hoofdauteurs: Murakami-Sekimata, Akiko, Huang, Dongqing, Piening, Brian D., Bangur, Chaitanya, Paulovich, Amanda G.
Formaat: Artigo
Taal:Inglês
Gepubliceerd in: 2010
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Online toegang:https://ncbi.nlm.nih.gov/pmc/articles/PMC2893243/
https://ncbi.nlm.nih.gov/pubmed/20472512
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1016/j.dnarep.2010.04.007
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