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The Preference for Error-Free or Error-Prone Postreplication Repair in Saccharomyces cerevisiae Exposed to Low-Dose Methyl Methanesulfonate Is Cell Cycle Dependent

Cells employ error-free or error-prone postreplication repair (PRR) processes to tolerate DNA damage. Here, we present a genome-wide screen for sensitivity to 0.001% methyl methanesulfonate (MMS). This relatively low dose is of particular interest because wild-type cells exhibit no discernible pheno...

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Autors principals: Huang, Dongqing, Piening, Brian D., Paulovich, Amanda G.
Format: Artigo
Idioma:Inglês
Publicat: American Society for Microbiology 2013
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Accés en línia:https://ncbi.nlm.nih.gov/pmc/articles/PMC3624245/
https://ncbi.nlm.nih.gov/pubmed/23382077
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1128/MCB.01392-12
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