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Structural Basis of Gate-DNA Breakage and Resealing by Type II Topoisomerases
Type II DNA topoisomerases are ubiquitous enzymes with essential functions in DNA replication, recombination and transcription. They change DNA topology by forming a transient covalent cleavage complex with a gate-DNA duplex that allows transport of a second duplex though the gate. Despite its biolo...
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| Главные авторы: | , , , , , |
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| Формат: | Artigo |
| Язык: | Inglês |
| Опубликовано: |
Public Library of Science
2010
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| Предметы: | |
| Online-ссылка: | https://ncbi.nlm.nih.gov/pmc/articles/PMC2893164/ https://ncbi.nlm.nih.gov/pubmed/20596531 https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1371/journal.pone.0011338 |
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