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The polyubiquitin Ubc gene modulates histone H2A monoubiquitylation in the R6/2 mouse model of Huntington's disease

Huntington's disease (HD) is an inherited neurodegenerative disease caused by the expansion of a polyglutamine tract in the protein huntingtin (htt). HD brains are characterized by the presence of ubiquitin‐positive neuronal inclusion bodies, suggesting that disturbances in the distribution of...

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Bibliografiska uppgifter
Huvudupphovsmän: Bett, John S., Benn, Caroline L., Ryu, Kwon‐Yul, Kopito, Ron R., Bates, Gillian P.
Materialtyp: Artigo
Språk:Inglês
Publicerad: Blackwell Publishing Ltd 2008
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Länkar:https://ncbi.nlm.nih.gov/pmc/articles/PMC2892477/
https://ncbi.nlm.nih.gov/pubmed/19602042
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1111/j.1582-4934.2008.00543.x
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