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The Mouse Polyubiquitin Gene Ubb Is Essential for Meiotic Progression

Ubiquitin is encoded in mice by two polyubiquitin genes, Ubb and Ubc, that are considered to be stress inducible and two constitutively expressed monoubiquitin (Uba) genes. Here we report that targeted disruption of Ubb results in male and female infertility due to failure of germ cells to progress...

詳細記述

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書誌詳細
主要な著者: Ryu, Kwon-Yul, Sinnar, Shamim A., Reinholdt, Laura G., Vaccari, Sergio, Hall, Susan, Garcia, Manuel A., Zaitseva, Tatiana S., Bouley, Donna M., Boekelheide, Kim, Handel, Mary Ann, Conti, Marco, Kopito, Ron R.
フォーマット: Artigo
言語:Inglês
出版事項: American Society for Microbiology (ASM) 2008
主題:
オンライン・アクセス:https://ncbi.nlm.nih.gov/pmc/articles/PMC2223379/
https://ncbi.nlm.nih.gov/pubmed/18070917
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1128/MCB.01566-07
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