The Mouse Polyubiquitin Gene Ubb Is Essential for Meiotic Progression

Ubiquitin is encoded in mice by two polyubiquitin genes, Ubb and Ubc, that are considered to be stress inducible and two constitutively expressed monoubiquitin (Uba) genes. Here we report that targeted disruption of Ubb results in male and female infertility due to failure of germ cells to progress...

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Hlavní autoři: Ryu, Kwon-Yul, Sinnar, Shamim A., Reinholdt, Laura G., Vaccari, Sergio, Hall, Susan, Garcia, Manuel A., Zaitseva, Tatiana S., Bouley, Donna M., Boekelheide, Kim, Handel, Mary Ann, Conti, Marco, Kopito, Ron R.
Médium: Artigo
Jazyk:Inglês
Vydáno: American Society for Microbiology (ASM) 2008
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On-line přístup:https://ncbi.nlm.nih.gov/pmc/articles/PMC2223379/
https://ncbi.nlm.nih.gov/pubmed/18070917
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1128/MCB.01566-07
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