Genetic Modulation of GABA Levels in the Anterior Cingulate Cortex by GAD1 and COMT

γ-Aminobutyric acid (GABA)-ergic transmission is critical for normal cortical function and is likely abnormal in a variety of neuropsychiatric disorders. We tested the in vivo effects of variations in two genes implicated in GABA function on GABA concentrations in prefrontal cortex of living subject...

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Main Authors: Marenco, Stefano, Savostyanova, Antonina A, van der Veen, Jan Willem, Geramita, Matthew, Stern, Alexa, Barnett, Alan S, Kolachana, Bhaskar, Radulescu, Eugenia, Zhang, Fengyu, Callicott, Joseph H, Straub, Richard E, Shen, Jun, Weinberger, Daniel R
Formato: Artigo
Idioma:Inglês
Publicado: Nature Publishing Group 2010
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Original Article
Acceso en liña:https://ncbi.nlm.nih.gov/pmc/articles/PMC2891897/
https://ncbi.nlm.nih.gov/pubmed/20357758
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1038/npp.2010.35
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