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Darinaparsin Induces a Unique Cellular Response and is Active in an Arsenic Trioxide-Resistant Myeloma Cell Line
Here we report on organic arsenical darinaparsin (DAR, ZIO-101, S-dimethylarsino-glutathione) and its anti-myeloma activity compared with inorganic arsenic trioxide (ATO). Darinaparsin induced apoptosis in multiple myeloma cell lines in a dose-dependent manner, and the addition of N-acetylcysteine,...
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| Main Authors: | , , , , , , , |
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| Formato: | Artigo |
| Idioma: | Inglês |
| Publicado: |
2009
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| Assuntos: | |
| Acceso en liña: | https://ncbi.nlm.nih.gov/pmc/articles/PMC2891844/ https://ncbi.nlm.nih.gov/pubmed/19417148 https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1158/1535-7163.MCT-08-1072 |
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