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p70 Ribosomal S6 Kinase Is Required for Airway Smooth Muscle Cell Size Enlargement but Not Increased Contractile Protein Expression
We examined the contribution of p70 ribosomal S6 kinase (p70S6K) to airway smooth muscle hypertrophy, a structural change found in asthma. In human airway smooth muscle cells, transforming growth factor (TGF)-β, endothelin-1, and cardiotrophin-1 each induced phosphorylation of p70S6K and ribosomal p...
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| Main Authors: | , , , , , , |
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| Formato: | Artigo |
| Idioma: | Inglês |
| Publicado em: |
American Thoracic Society
2010
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| Assuntos: | |
| Acesso em linha: | https://ncbi.nlm.nih.gov/pmc/articles/PMC2891500/ https://ncbi.nlm.nih.gov/pubmed/19648476 https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1165/rcmb.2009-0037OC |
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