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Pulmonary artery smooth muscle hypertrophy: roles of glycogen synthase kinase-3β and p70 ribosomal S6 kinase

Increased medial arterial thickness is a structural change in pulmonary arterial hypertension (PAH). The role of smooth muscle hypertrophy in this process has not been well studied. Bone morphogenetic proteins (BMPs), transforming growth factor (TGF)-β1, serotonin (or 5-hydroxytryptamine; 5-HT), and...

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Bibliografische gegevens
Hoofdauteurs: Deng, Huan, Hershenson, Marc B., Lei, Jing, Anyanwu, Anuli C., Pinsky, David J., Bentley, J. Kelley
Formaat: Artigo
Taal:Inglês
Gepubliceerd in: American Physiological Society 2010
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Online toegang:https://ncbi.nlm.nih.gov/pmc/articles/PMC4073898/
https://ncbi.nlm.nih.gov/pubmed/20190034
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1152/ajplung.00108.2009
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