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tRNA(His) maturation: An essential yeast protein catalyzes addition of a guanine nucleotide to the 5′ end of tRNA(His)

All tRNA(His) molecules are unusual in having an extra 5′ GMP residue (G(-1)) that, in eukaryotes, is added after transcription and RNase P cleavage. Incorporation of this G(-1) residue is a rare example of nucleotide addition occurring at an RNA 5′ end in a normal phosphodiester linkage. We show he...

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Main Authors: Gu, Weifeng, Jackman, Jane E., Lohan, Amanda J., Gray, Michael W., Phizicky, Eric M.
Format: Artigo
Jezik:Inglês
Izdano: Cold Spring Harbor Laboratory Press 2003
Teme:
Online dostop:https://ncbi.nlm.nih.gov/pmc/articles/PMC289149/
https://ncbi.nlm.nih.gov/pubmed/14633974
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1101/gad.1148603
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