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Kinetic analysis of 3′-5′ nucleotide addition catalyzed by eukaryotic tRNA(His) guanylyltransferase()

The tRNA(His) guanylyltransferase (Thg1) catalyzes the incorporation of a single guanosine residue to the −1 position (G(−1)) of tRNA(His), using an unusual 3′-5′ nucleotidyl transfer reaction. Thg1 and Thg1 orthologs known as Thg1-like proteins (TLPs), which catalyze tRNA repair and editing, are th...

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Detalhes bibliográficos
Main Authors: Smith, Brian A., Jackman, Jane E.
Formato: Artigo
Idioma:Inglês
Publicado em: 2011
Assuntos:
Acesso em linha:https://ncbi.nlm.nih.gov/pmc/articles/PMC3254824/
https://ncbi.nlm.nih.gov/pubmed/22136300
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1021/bi201397f
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