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tRNA(His) maturation: An essential yeast protein catalyzes addition of a guanine nucleotide to the 5′ end of tRNA(His)

All tRNA(His) molecules are unusual in having an extra 5′ GMP residue (G(-1)) that, in eukaryotes, is added after transcription and RNase P cleavage. Incorporation of this G(-1) residue is a rare example of nucleotide addition occurring at an RNA 5′ end in a normal phosphodiester linkage. We show he...

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Publicat a:Genes Dev
Autors principals: Gu, Weifeng, Jackman, Jane E., Lohan, Amanda J., Gray, Michael W., Phizicky, Eric M.
Format: Artigo
Idioma:Inglês
Publicat: Cold Spring Harbor Laboratory Press 2003
Matèries:
Accés en línia:https://ncbi.nlm.nih.govhttps://pmc.ncbi.nlm.nih.gov/articles/PMC289149/
https://ncbi.nlm.nih.govhttps://pubmed.ncbi.nlm.nih.gov/14633974/
https://ncbi.nlm.nih.govhttps://doi.org/10.1101/gad.1148603
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