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Protein Folding Requires Crowd Control in a Simulated Cell

Macromolecular crowding has a profound effect upon biochemical processes in the cell. We have computationally studied the effect of crowding upon protein folding for 12 small domains in a simulated cell using a coarse-grained protein model, which is based upon Langevin dynamics, designed to unify th...

Ausführliche Beschreibung

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Bibliographische Detailangaben
Hauptverfasser: Jefferys, Benjamin R., Kelley, Lawrence A., Sternberg, Michael J.E.
Format: Artigo
Sprache:Inglês
Veröffentlicht: Elsevier 2010
Schlagworte:
Online Zugang:https://ncbi.nlm.nih.gov/pmc/articles/PMC2891488/
https://ncbi.nlm.nih.gov/pubmed/20149797
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1016/j.jmb.2010.01.074
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