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Protein Folding Requires Crowd Control in a Simulated Cell
Macromolecular crowding has a profound effect upon biochemical processes in the cell. We have computationally studied the effect of crowding upon protein folding for 12 small domains in a simulated cell using a coarse-grained protein model, which is based upon Langevin dynamics, designed to unify th...
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Main Authors: | , , |
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Formato: | Artigo |
Idioma: | Inglês |
Publicado em: |
Elsevier
2010
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Assuntos: | |
Acesso em linha: | https://ncbi.nlm.nih.gov/pmc/articles/PMC2891488/ https://ncbi.nlm.nih.gov/pubmed/20149797 https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1016/j.jmb.2010.01.074 |
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