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Reduced Nitro-oxidative Stress and Neural Cell Death Suggests a Protective Role for Microglial Cells in TNFα(−/−) Mice in Ischemic Retinopathy

PURPOSE. Neovascularization occurs in response to tissue ischemia and growth factor stimulation. In ischemic retinopathies, however, new vessels fail to restore the hypoxic tissue; instead, they infiltrate the transparent vitreous. In a model of oxygen-induced retinopathy (OIR), TNFα and iNOS, upreg...

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Autori principali: Stevenson, Laura, Matesanz, Nuria, Colhoun, Liza, Edgar, Kevin, Devine, Adrian, Gardiner, Tom A., McDonald, Denise M.
Natura: Artigo
Lingua:Inglês
Pubblicazione: Association for Research in Vision and Ophthalmology, Inc. 2010
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Accesso online:https://ncbi.nlm.nih.gov/pmc/articles/PMC2891480/
https://ncbi.nlm.nih.gov/pubmed/20107169
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1167/iovs.09-4344
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