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Treatment with polyamine oxidase inhibitor reduces microglial activation and limits vascular injury in ischemic retinopathy

Retinal vascular injury is a major cause of vision impairment in ischemic retinopathies. Insults such as hyperoxia, oxidative stress and inflammation contribute to this pathology. Previously, we showed that hyperoxia-induced retinal neurodegeneration is associated with increased polyamine oxidation....

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Podrobná bibliografie
Vydáno v:Biochim Biophys Acta
Hlavní autoři: Patel, C., Xu, Z., Shosha, E., Xing, J., Lucas, R., Caldwell, R.W., Caldwell, R.B., Narayanan, S.P.
Médium: Artigo
Jazyk:Inglês
Vydáno: 2016
Témata:
On-line přístup:https://ncbi.nlm.nih.gov/pmc/articles/PMC5091072/
https://ncbi.nlm.nih.gov/pubmed/27239699
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1016/j.bbadis.2016.05.020
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