Inhibition of NAD(P)H Oxidase Activity Blocks Vascular Endothelial Growth Factor Overexpression and Neovascularization during Ischemic Retinopathy

Because oxidative stress has been strongly implicated in up-regulation of vascular endothelial growth factor (VEGF) expression in ischemic retinopathy, we evaluated the role of NAD(P)H oxidase in causing VEGF overexpression and retinal neovascularization. Dihydroethidium imaging analyses showed incr...

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Detalhes bibliográficos
Main Authors: Al-Shabrawey, Mohamed, Bartoli, Manuela, El-Remessy, Azza B., Platt, Daniel H., Matragoon, Sue, Behzadian, M. Ali, Caldwell, Robert W., Caldwell, Ruth B.
Formato: Artigo
Idioma:Inglês
Publicado em: American Society for Investigative Pathology 2005
Assuntos:
Original Research Paper
Acesso em linha:https://ncbi.nlm.nih.gov/pmc/articles/PMC1603550/
https://ncbi.nlm.nih.gov/pubmed/16049343
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