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Inhibition of Tumor Necrosis Factor-α Improves Physiological Angiogenesis and Reduces Pathological Neovascularization in Ischemic Retinopathy
The present study was undertaken to test whether inhibition of the proangiogenic inflammatory cytokine tumor necrosis factor (TNF)-α can modulate retinal hypoxia and preretinal neovascularization in a murine model of oxygen-induced retinopathy (OIR). OIR was produced in TNF-α−/− and wild-type (WT) c...
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| Main Authors: | , , , , , |
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| Formato: | Artigo |
| Idioma: | Inglês |
| Publicado em: |
American Society for Investigative Pathology
2005
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| Assuntos: | |
| Acesso em linha: | https://ncbi.nlm.nih.gov/pmc/articles/PMC1602321/ https://ncbi.nlm.nih.gov/pubmed/15681845 |
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