The Regulatory NOD-Like Receptor NLRC5 Promotes Ganglion Cell Death in Ischemic Retinopathy by Inducing Microglial Pyroptosis

Retinal ischemia is a common pathological event that can result in retinal ganglion cell (RGC) death and irreversible vision loss. The pathogenic mechanisms linking retinal ischemia to RGC loss and visual deficits are uncertain, which has greatly hampered the development of effective treatments. It...

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Bibliografiska uppgifter
I publikationen:Front Cell Dev Biol
Huvudupphovsmän: Deng, Yang, Fu, Yunzhao, Sheng, Longxiang, Hu, Yixin, Su, Lishi, Luo, Jiawen, Yan, Chun, Chi, Wei
Materialtyp: Artigo
Språk:Inglês
Publicerad: Frontiers Media S.A. 2021
Ämnen:
Cell and Developmental Biology
Länkar:https://ncbi.nlm.nih.gov/pmc/articles/PMC8173141/
https://ncbi.nlm.nih.gov/pubmed/34095138
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.3389/fcell.2021.669696
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