NLRP12 collaborates with NLRP3 and NLRC4 to promote pyroptosis inducing ganglion cell death of acute glaucoma

BACKGROUND: Acute glaucoma, characterized by a sudden elevation in intraocular pressure (IOP) and retinal ganglion cells (RGCs) death, is a major cause of irreversible blindness worldwide that lacks approved effective therapies, validated treatment targets and clear molecular mechanisms. We sought t...

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Dades bibliogràfiques
Publicat a:Mol Neurodegener
Autors principals: Chen, Hui, Deng, Yang, Gan, Xiaoliang, Li, Yonghao, Huang, Wenyong, Lu, Lin, Wei, Lai, Su, Lishi, Luo, Jiawen, Zou, Bin, Hong, Yanhua, Cao, Yihai, Liu, Yizhi, Chi, Wei
Format: Artigo
Idioma:Inglês
Publicat: BioMed Central 2020
Matèries:
Research Article
Accés en línia:https://ncbi.nlm.nih.gov/pmc/articles/PMC7161290/
https://ncbi.nlm.nih.gov/pubmed/32295623
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1186/s13024-020-00372-w
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