NLRP3 recruitment by NLRC4 during Salmonella infection

NLRC4 and NLRP3, of the NOD-like receptor (NLR) family of intracellular proteins, are expressed in innate immune cells and are thought to nucleate distinct inflammasome complexes that promote caspase-1 activation, secretion of the proinflammatory cytokines IL-1β and IL-18, and a form of cell death t...

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Bibliographische Detailangaben
Veröffentlicht in:J Exp Med
Hauptverfasser: Qu, Yan, Misaghi, Shahram, Newton, Kim, Maltzman, Allie, Izrael-Tomasevic, Anita, Arnott, David, Dixit, Vishva M.
Format: Artigo
Sprache:Inglês
Veröffentlicht: The Rockefeller University Press 2016
Schlagworte:
Research Articles
Online Zugang:https://ncbi.nlm.nih.gov/pmc/articles/PMC4886354/
https://ncbi.nlm.nih.gov/pubmed/27139490
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1084/jem.20132234
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