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Contributions of β2-microglobulin–dependent molecules and lymphocytes to iron regulation: insights from HfeRag1(−/−) and β2mRag1(−/−) double knock-out mice

Genetic causes of hereditary hemochromatosis (HH) include mutations in the HFE gene, coding for a β2-microglobulin (β2m)–associated major histocompatibility complex class I-like protein. However, iron accumulation in patients with HH can be highly variable. Previously, analysis of β2mRag1(−/−) doubl...

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Detalhes bibliográficos
Main Authors: Miranda, Carlos J., Makui, Hortence, Andrews, Nancy C., Santos, Manuela M.
Formato: Artigo
Idioma:Inglês
Publicado em: 2003
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Acesso em linha:https://ncbi.nlm.nih.gov/pmc/articles/PMC2891006/
https://ncbi.nlm.nih.gov/pubmed/14656877
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1182/blood-2003-09-3300
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