One SUMO is sufficient to silence the dimeric potassium channel K2P1

Small ubiquitin modifier 1 (SUMO1) is shown to regulate K2P1 background channels in the plasma membrane (PM) of live mammalian cells. Confocal microscopy reveals native SUMO1, SAE1, and Ubc9 (the enzymes that activate and conjugate SUMO1) at PM where SUMO1 and expressed human K2P1 are demonstrated t...

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Bibliografiske detaljer
Main Authors: Plant, Leigh D., Dementieva, Irina S., Kollewe, Astrid, Olikara, Sonia, Marks, Jeremy D., Goldstein, Steve A. N.
Format: Artigo
Sprog:Inglês
Udgivet: National Academy of Sciences 2010
Fag:
Biological Sciences
Online adgang:https://ncbi.nlm.nih.gov/pmc/articles/PMC2890841/
https://ncbi.nlm.nih.gov/pubmed/20498050
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1073/pnas.1004712107
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