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A structural model for K(2P) potassium channels based on 23 pairs of interacting sites and continuum electrostatics
K(2P)Ø, the two-pore domain potassium background channel that determines cardiac rhythm in Drosophila melanogaster, and its homologues that establish excitable membrane activity in mammals are of unknown structure. K(2P) subunits have two pore domains flanked by transmembrane (TM) spans: TM1-P1-TM2-...
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| Main Authors: | , , , , |
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| Formato: | Artigo |
| Idioma: | Inglês |
| Publicado em: |
The Rockefeller University Press
2009
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| Assuntos: | |
| Acesso em linha: | https://ncbi.nlm.nih.gov/pmc/articles/PMC2712977/ https://ncbi.nlm.nih.gov/pubmed/19564427 https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1085/jgp.200910235 |
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