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A structural model for K(2P) potassium channels based on 23 pairs of interacting sites and continuum electrostatics
K(2P)Ø, the two-pore domain potassium background channel that determines cardiac rhythm in Drosophila melanogaster, and its homologues that establish excitable membrane activity in mammals are of unknown structure. K(2P) subunits have two pore domains flanked by transmembrane (TM) spans: TM1-P1-TM2-...
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| Main Authors: | , , , , |
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| פורמט: | Artigo |
| שפה: | Inglês |
| יצא לאור: |
The Rockefeller University Press
2009
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| נושאים: | |
| גישה מקוונת: | https://ncbi.nlm.nih.gov/pmc/articles/PMC2712977/ https://ncbi.nlm.nih.gov/pubmed/19564427 https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1085/jgp.200910235 |
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