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Conversion of a yeast prion protein to an infectious form in bacteria

Prions are infectious, self-propagating protein aggregates that have been identified in evolutionarily divergent members of the eukaryotic domain of life. Nevertheless, it is not yet known whether prokaryotes can support the formation of prion aggregates. Here we demonstrate that the yeast prion pro...

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Bibliographic Details
Main Authors: Garrity, Sean J., Sivanathan, Viknesh, Dong, Jijun, Lindquist, Susan, Hochschild, Ann
Format: Artigo
Language:Inglês
Published: National Academy of Sciences 2010
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Online Access:https://ncbi.nlm.nih.gov/pmc/articles/PMC2890818/
https://ncbi.nlm.nih.gov/pubmed/20484678
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1073/pnas.0913280107
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