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Hepadnavirus integration: mechanisms of activation of the N-myc2 retrotransposon in woodchuck liver tumors.

In persistent hepadnavirus infections, a distinctive feature of woodchuck hepatitis virus (WHV) is the coupling of frequent viral integrations into myc family genes with the rapid onset of primary liver tumors. We have investigated the patterns of WHV DNA insertion into N-myc2, a newly identified re...

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Détails bibliographiques
Publié dans:J Virol
Auteurs principaux: Wei, Y, Fourel, G, Ponzetto, A, Silvestro, M, Tiollais, P, Buendia, M A
Format: Artigo
Langue:Inglês
Publié: American Society for Microbiology (ASM) 1992
Sujets:
Accès en ligne:https://ncbi.nlm.nih.govhttps://pmc.ncbi.nlm.nih.gov/articles/PMC289080/
https://ncbi.nlm.nih.govhttps://pubmed.ncbi.nlm.nih.gov/1323693/
https://ncbi.nlm.nih.govhttps://doi.org/10.1128/jvi.66.9.5265-5276.1992
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