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Antisense Downregulation of N-myc1 in Woodchuck Hepatoma Cells Reverses the Malignant Phenotype

Cell line WH44KA is a highly malignant woodchuck hepatoma cell line. WH44KA cells contain a single woodchuck hepatitis virus (WHV) DNA integration in the 3′ untranslated region of exon 3 of the woodchuck N-myc1 gene. The highly rearranged WHV DNA contains WHV enhancers which activate the N-myc promo...

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Detalles Bibliográficos
Main Authors: Wang, Hai-Ping, Zhang, Lunli, Dandri, Maura, Rogler, Charles E.
Formato: Artigo
Idioma:Inglês
Publicado: American Society for Microbiology 1998
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Acceso en liña:https://ncbi.nlm.nih.gov/pmc/articles/PMC109515/
https://ncbi.nlm.nih.gov/pubmed/9499076
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