Woodchuck hepatitis virus X protein is present in chronically infected woodchuck liver and woodchuck hepatocellular carcinomas which are permissive for viral replication.

The woodchuck hepatitis virus (WHV) X gene (WHx) is required for infectivity of WHV in woodchucks, and the gene encodes a broadly acting transcription factor. Several lines of evidence from cell culture and transgenic mice suggest that X proteins can promote hepatocarcinogenesis. To determine whethe...

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Detalhes bibliográficos

Publicado no:	J Virol
Principais autores:	Dandri, M, Schirmacher, P, Rogler, C E
Formato:	Artigo
Idioma:	Inglês
Publicado em:	American Society for Microbiology (ASM) 1996
Assuntos:	Research Article
Acesso em linha:	https://ncbi.nlm.nih.govhttps://pmc.ncbi.nlm.nih.gov/articles/PMC190481/ https://ncbi.nlm.nih.govhttps://pubmed.ncbi.nlm.nih.gov/8764034/ https://ncbi.nlm.nih.govhttps://doi.org/10.1128/jvi.70.8.5246-5254.1996
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