Hepadnavirus integration: mechanisms of activation of the N-myc2 retrotransposon in woodchuck liver tumors.

In persistent hepadnavirus infections, a distinctive feature of woodchuck hepatitis virus (WHV) is the coupling of frequent viral integrations into myc family genes with the rapid onset of primary liver tumors. We have investigated the patterns of WHV DNA insertion into N-myc2, a newly identified re...

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Main Authors: Wei, Y, Fourel, G, Ponzetto, A, Silvestro, M, Tiollais, P, Buendia, M A
Formato: Artigo
Idioma:Inglês
Publicado: 1992
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Research Article
Acceso en liña:https://ncbi.nlm.nih.gov/pmc/articles/PMC289080/
https://ncbi.nlm.nih.gov/pubmed/1323693
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