Chargement en cours...
The apical transmembrane protein Crumbs functions as a tumor suppressor that regulates Hippo signaling by binding to Expanded
The Hippo signaling pathway regulates organ size and tissue homeostasis from Drosophila to mammals. At the core of the Hippo pathway is a kinase cascade extending from the Hippo (Hpo) tumor suppressor to the Yorkie (Yki) oncoprotein. The Hippo kinase cascade, in turn, is regulated by apical membrane...
Enregistré dans:
| Auteurs principaux: | , , , , , , , |
|---|---|
| Format: | Artigo |
| Langue: | Inglês |
| Publié: |
National Academy of Sciences
2010
|
| Sujets: | |
| Accès en ligne: | https://ncbi.nlm.nih.gov/pmc/articles/PMC2890787/ https://ncbi.nlm.nih.gov/pubmed/20498073 https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1073/pnas.1004279107 |
| Tags: |
Ajouter un tag
Pas de tags, Soyez le premier à ajouter un tag!
|