The apical transmembrane protein Crumbs functions as a tumor suppressor that regulates Hippo signaling by binding to Expanded

The Hippo signaling pathway regulates organ size and tissue homeostasis from Drosophila to mammals. At the core of the Hippo pathway is a kinase cascade extending from the Hippo (Hpo) tumor suppressor to the Yorkie (Yki) oncoprotein. The Hippo kinase cascade, in turn, is regulated by apical membrane...

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Detaylı Bibliyografya
Asıl Yazarlar: Ling, Chen, Zheng, Yonggang, Yin, Feng, Yu, Jianzhong, Huang, Juan, Hong, Yang, Wu, Shian, Pan, Duojia
Materyal Türü: Artigo
Dil:Inglês
Baskı/Yayın Bilgisi: National Academy of Sciences 2010
Konular:
Biological Sciences
Online Erişim:https://ncbi.nlm.nih.gov/pmc/articles/PMC2890787/
https://ncbi.nlm.nih.gov/pubmed/20498073
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1073/pnas.1004279107
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