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Spatial organization of Hippo signaling at the plasma membrane mediated by the tumor suppressor Merlin/NF2
Although Merlin/NF2 was discovered two decades ago as a tumor suppressor underlying Neurofibromatosis type II, its precise molecular mechanism remains poorly understood. Recent studies in Drosophila revealed a potential link between Merlin and the Hippo pathway by placing Merlin genetically upstream...
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| Main Authors: | , , , , , |
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| Formato: | Artigo |
| Idioma: | Inglês |
| Publicado em: |
2013
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| Assuntos: | |
| Acesso em linha: | https://ncbi.nlm.nih.gov/pmc/articles/PMC3835333/ https://ncbi.nlm.nih.gov/pubmed/24012335 https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1016/j.cell.2013.08.025 |
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