The Hippo effector Yorkie controls normal tissue growth by antagonizing Scalloped-mediated default repression

The Hippo tumor suppressor pathway restricts tissue growth by inactivating the transcriptional coactivator Yki. Although Sd has been implicated as a DNA-binding transcription factor partner for Yki and can genetically account for gain-of-function Yki phenotypes, how Yki regulates normal tissue growt...

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Bibliografske podrobnosti
Main Authors: Koontz, Laura M., Liu-Chittenden, Yi, Yin, Feng, Zheng, Yonggang, Yu, Jianzhong, Huang, Bo, Chen, Qian, Wu, Shian, Pan, Duojia
Format: Artigo
Jezik:Inglês
Izdano: 2013
Teme:
Article
Online dostop:https://ncbi.nlm.nih.gov/pmc/articles/PMC3705890/
https://ncbi.nlm.nih.gov/pubmed/23725764
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1016/j.devcel.2013.04.021
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