Constitutively decreased TGFBR1 allelic expression is a common finding in colorectal cancer and is associated with three TGFBR1 SNPs

PURPOSE: Constitutively decreased TGFBR1 allelic expression is emerging as a potent modifier of colorectal cancer risk in mice and humans. This phenotype was first observed in mice, then in lymphoblastoid cell lines from patients with microsatellite stable colorectal tumors. PATIENTS AND METHODS: We...

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Bibliografiset tiedot
Päätekijät: Pasche, Boris, Wisinski, Kari B, Sadim, Maureen, Kaklamani, Virginia, Pennison, Michael J, Zeng, Qinghua, Bellam, Naresh, Zimmerman, Jacquelyn, Yi, Nengjun, Zhang, Kui, Baron, John, Stram, Daniel O, Hayes, M Geoffrey
Aineistotyyppi: Artigo
Kieli:Inglês
Julkaistu: BioMed Central 2010
Aiheet:
Research
Linkit:https://ncbi.nlm.nih.gov/pmc/articles/PMC2890549/
https://ncbi.nlm.nih.gov/pubmed/20500843
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1186/1756-9966-29-57
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