Constitutively decreased TGFBR1 allelic expression is a common finding in colorectal cancer and is associated with three TGFBR1 SNPs

PURPOSE: Constitutively decreased TGFBR1 allelic expression is emerging as a potent modifier of colorectal cancer risk in mice and humans. This phenotype was first observed in mice, then in lymphoblastoid cell lines from patients with microsatellite stable colorectal tumors. PATIENTS AND METHODS: We...

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Detalhes bibliográficos
Main Authors: Pasche, Boris, Wisinski, Kari B, Sadim, Maureen, Kaklamani, Virginia, Pennison, Michael J, Zeng, Qinghua, Bellam, Naresh, Zimmerman, Jacquelyn, Yi, Nengjun, Zhang, Kui, Baron, John, Stram, Daniel O, Hayes, M Geoffrey
Formato: Artigo
Idioma:Inglês
Publicado em: BioMed Central 2010
Assuntos:
Research
Acesso em linha:https://ncbi.nlm.nih.gov/pmc/articles/PMC2890549/
https://ncbi.nlm.nih.gov/pubmed/20500843
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1186/1756-9966-29-57
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