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Somatic acquisition of TGFBR1*6A by epithelial and stromal cells during head and neck and colon cancer development
TGFBR1*6A is a common hypomorphic variant of the type I transforming growth factor (TGF)-β receptor (TGFBR1), which transduces TGF-β growth inhibitory signals less effectively than TGFBR1. Recent studies suggest that TGFBR1*6A confers a selective growth advantage to both normal appearing and cancero...
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| Main Authors: | , , , , , , , |
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| Formato: | Artigo |
| Idioma: | Inglês |
| Publicado em: |
2007
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| Assuntos: | |
| Acesso em linha: | https://ncbi.nlm.nih.gov/pmc/articles/PMC2637554/ https://ncbi.nlm.nih.gov/pubmed/17890272 https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1093/hmg/ddm274 |
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